Can genetic modifications become hereditary?

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Could genetic modifications become hereditary over time? If so could they evolve over time similar to regular genes? For example making carbon fibre bones for whatever reason would they eventually become a regular genetic trait?










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    by definition if it is genetic it s already a regular hereditary trait. As long as the germ cells are also altered it will be passed on. I'm not really sure what you are asking.
    – John
    2 hours ago















up vote
2
down vote

favorite












Could genetic modifications become hereditary over time? If so could they evolve over time similar to regular genes? For example making carbon fibre bones for whatever reason would they eventually become a regular genetic trait?










share|improve this question

















  • 1




    by definition if it is genetic it s already a regular hereditary trait. As long as the germ cells are also altered it will be passed on. I'm not really sure what you are asking.
    – John
    2 hours ago













up vote
2
down vote

favorite









up vote
2
down vote

favorite











Could genetic modifications become hereditary over time? If so could they evolve over time similar to regular genes? For example making carbon fibre bones for whatever reason would they eventually become a regular genetic trait?










share|improve this question













Could genetic modifications become hereditary over time? If so could they evolve over time similar to regular genes? For example making carbon fibre bones for whatever reason would they eventually become a regular genetic trait?







evolution genetics genetic-engineering






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asked 2 hours ago









user93310

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735







  • 1




    by definition if it is genetic it s already a regular hereditary trait. As long as the germ cells are also altered it will be passed on. I'm not really sure what you are asking.
    – John
    2 hours ago













  • 1




    by definition if it is genetic it s already a regular hereditary trait. As long as the germ cells are also altered it will be passed on. I'm not really sure what you are asking.
    – John
    2 hours ago








1




1




by definition if it is genetic it s already a regular hereditary trait. As long as the germ cells are also altered it will be passed on. I'm not really sure what you are asking.
– John
2 hours ago





by definition if it is genetic it s already a regular hereditary trait. As long as the germ cells are also altered it will be passed on. I'm not really sure what you are asking.
– John
2 hours ago











2 Answers
2






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6
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If the modification happens on someone's germline cells, it becomes hereditary.



Notice that modifying zygotes, or an embryo, tends to have much the same effect, since germline cells will develop from those.



Once it becomes hereditary, such modified genes will follow all the same rules as any other genes.



Remember, every single gene existing in nature today is a mutation from some previous gene, all the way back in history to the very first RNA strand.




If you're just doing something localized though, like infecting only your liver with a modified adenovirus to get more alcohol resistance, then your kids probably won't get it from you.






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  • Shouldn't "gonad cells" be "germline cells"?
    – AlexP
    2 hours ago










  • @AlexP yes, thanks for the tip :)
    – Renan
    2 hours ago










  • +1. FWIW, this is also the case for epigenetics
    – Punintended
    37 mins ago

















up vote
1
down vote













They can. Maybe.



As @Renan pointed out, as long as you modify the eggs and the sperm producing cells, it can be passed on.



However, and this is the big question:



Can the embryo and/or the infant survive with the modifications. A lot happens in the first few weeks (and then over the first few years).



The common thought is that even zero-G will interfere with the development of the fetus because the chemical processes are so balanced for the process in 1G. It would take careful experimentation or great luck to get genetic modifications that allow for a viable fetus.



After birth there is a lot happening in a growing child. For example: if they grow too fast, their joints may not develop properly. Then we get into puberty and everything that happens then.



So, my answer is it is possible but not probable.






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    2 Answers
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    2 Answers
    2






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    up vote
    6
    down vote













    If the modification happens on someone's germline cells, it becomes hereditary.



    Notice that modifying zygotes, or an embryo, tends to have much the same effect, since germline cells will develop from those.



    Once it becomes hereditary, such modified genes will follow all the same rules as any other genes.



    Remember, every single gene existing in nature today is a mutation from some previous gene, all the way back in history to the very first RNA strand.




    If you're just doing something localized though, like infecting only your liver with a modified adenovirus to get more alcohol resistance, then your kids probably won't get it from you.






    share|improve this answer






















    • Shouldn't "gonad cells" be "germline cells"?
      – AlexP
      2 hours ago










    • @AlexP yes, thanks for the tip :)
      – Renan
      2 hours ago










    • +1. FWIW, this is also the case for epigenetics
      – Punintended
      37 mins ago














    up vote
    6
    down vote













    If the modification happens on someone's germline cells, it becomes hereditary.



    Notice that modifying zygotes, or an embryo, tends to have much the same effect, since germline cells will develop from those.



    Once it becomes hereditary, such modified genes will follow all the same rules as any other genes.



    Remember, every single gene existing in nature today is a mutation from some previous gene, all the way back in history to the very first RNA strand.




    If you're just doing something localized though, like infecting only your liver with a modified adenovirus to get more alcohol resistance, then your kids probably won't get it from you.






    share|improve this answer






















    • Shouldn't "gonad cells" be "germline cells"?
      – AlexP
      2 hours ago










    • @AlexP yes, thanks for the tip :)
      – Renan
      2 hours ago










    • +1. FWIW, this is also the case for epigenetics
      – Punintended
      37 mins ago












    up vote
    6
    down vote










    up vote
    6
    down vote









    If the modification happens on someone's germline cells, it becomes hereditary.



    Notice that modifying zygotes, or an embryo, tends to have much the same effect, since germline cells will develop from those.



    Once it becomes hereditary, such modified genes will follow all the same rules as any other genes.



    Remember, every single gene existing in nature today is a mutation from some previous gene, all the way back in history to the very first RNA strand.




    If you're just doing something localized though, like infecting only your liver with a modified adenovirus to get more alcohol resistance, then your kids probably won't get it from you.






    share|improve this answer














    If the modification happens on someone's germline cells, it becomes hereditary.



    Notice that modifying zygotes, or an embryo, tends to have much the same effect, since germline cells will develop from those.



    Once it becomes hereditary, such modified genes will follow all the same rules as any other genes.



    Remember, every single gene existing in nature today is a mutation from some previous gene, all the way back in history to the very first RNA strand.




    If you're just doing something localized though, like infecting only your liver with a modified adenovirus to get more alcohol resistance, then your kids probably won't get it from you.







    share|improve this answer














    share|improve this answer



    share|improve this answer








    edited 2 hours ago

























    answered 2 hours ago









    Renan

    33.4k875171




    33.4k875171











    • Shouldn't "gonad cells" be "germline cells"?
      – AlexP
      2 hours ago










    • @AlexP yes, thanks for the tip :)
      – Renan
      2 hours ago










    • +1. FWIW, this is also the case for epigenetics
      – Punintended
      37 mins ago
















    • Shouldn't "gonad cells" be "germline cells"?
      – AlexP
      2 hours ago










    • @AlexP yes, thanks for the tip :)
      – Renan
      2 hours ago










    • +1. FWIW, this is also the case for epigenetics
      – Punintended
      37 mins ago















    Shouldn't "gonad cells" be "germline cells"?
    – AlexP
    2 hours ago




    Shouldn't "gonad cells" be "germline cells"?
    – AlexP
    2 hours ago












    @AlexP yes, thanks for the tip :)
    – Renan
    2 hours ago




    @AlexP yes, thanks for the tip :)
    – Renan
    2 hours ago












    +1. FWIW, this is also the case for epigenetics
    – Punintended
    37 mins ago




    +1. FWIW, this is also the case for epigenetics
    – Punintended
    37 mins ago










    up vote
    1
    down vote













    They can. Maybe.



    As @Renan pointed out, as long as you modify the eggs and the sperm producing cells, it can be passed on.



    However, and this is the big question:



    Can the embryo and/or the infant survive with the modifications. A lot happens in the first few weeks (and then over the first few years).



    The common thought is that even zero-G will interfere with the development of the fetus because the chemical processes are so balanced for the process in 1G. It would take careful experimentation or great luck to get genetic modifications that allow for a viable fetus.



    After birth there is a lot happening in a growing child. For example: if they grow too fast, their joints may not develop properly. Then we get into puberty and everything that happens then.



    So, my answer is it is possible but not probable.






    share|improve this answer
























      up vote
      1
      down vote













      They can. Maybe.



      As @Renan pointed out, as long as you modify the eggs and the sperm producing cells, it can be passed on.



      However, and this is the big question:



      Can the embryo and/or the infant survive with the modifications. A lot happens in the first few weeks (and then over the first few years).



      The common thought is that even zero-G will interfere with the development of the fetus because the chemical processes are so balanced for the process in 1G. It would take careful experimentation or great luck to get genetic modifications that allow for a viable fetus.



      After birth there is a lot happening in a growing child. For example: if they grow too fast, their joints may not develop properly. Then we get into puberty and everything that happens then.



      So, my answer is it is possible but not probable.






      share|improve this answer






















        up vote
        1
        down vote










        up vote
        1
        down vote









        They can. Maybe.



        As @Renan pointed out, as long as you modify the eggs and the sperm producing cells, it can be passed on.



        However, and this is the big question:



        Can the embryo and/or the infant survive with the modifications. A lot happens in the first few weeks (and then over the first few years).



        The common thought is that even zero-G will interfere with the development of the fetus because the chemical processes are so balanced for the process in 1G. It would take careful experimentation or great luck to get genetic modifications that allow for a viable fetus.



        After birth there is a lot happening in a growing child. For example: if they grow too fast, their joints may not develop properly. Then we get into puberty and everything that happens then.



        So, my answer is it is possible but not probable.






        share|improve this answer












        They can. Maybe.



        As @Renan pointed out, as long as you modify the eggs and the sperm producing cells, it can be passed on.



        However, and this is the big question:



        Can the embryo and/or the infant survive with the modifications. A lot happens in the first few weeks (and then over the first few years).



        The common thought is that even zero-G will interfere with the development of the fetus because the chemical processes are so balanced for the process in 1G. It would take careful experimentation or great luck to get genetic modifications that allow for a viable fetus.



        After birth there is a lot happening in a growing child. For example: if they grow too fast, their joints may not develop properly. Then we get into puberty and everything that happens then.



        So, my answer is it is possible but not probable.







        share|improve this answer












        share|improve this answer



        share|improve this answer










        answered 26 mins ago









        ShadoCat

        13.4k1848




        13.4k1848



























             

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